The Fujifilm Synapse Enterprise Imaging is a comprehensive enterprise-wide imaging informatics solution that integrates radiology, cardiology, pathology, specialty departments, mobility, AI, and analytics into a single, secure, and scalable platform. At its foundation, Synapse Enterprise PACS allows clinicians unrestricted access to diagnostic images across departments, securely storing both DICOM and non-DICOM data in a vendor-neutral archive (VNA). Radiology PACS extends beyond conventional functions by incorporating mammography tomosynthesis, advanced visualization, and AI-assisted interpretation, while Cardiology PACS streamlines echocardiography, catheterization, and nuclear cardiology through structured reporting and collaborative tools. Pathology PACS digitizes and accelerates workflows, enabling telepathology, interoperability, and FDA-cleared primary diagnosis from multiple scanners. A Mobility Enterprise Viewer provides anytime-anywhere access to diagnostic-grade images on any device, while Cloud Services ensure secure hosting, disaster recovery, and reduced IT burden. Enterprise Information Systems (EIS) improve patient engagement with self-scheduling, transparent cost tools, referrer portals, and streamlined order entry. The AI Orchestrator integrates a variety of algorithms into workflows, prioritizes urgent cases, and enhances diagnostic accuracy, while Synapse 3D delivers nearly 60 advanced visualization applications to support surgical planning and specialty interpretation. Complementing these is Synapse Analytics, which aggregates fragmented data into actionable insights, providing predictive views of procedure volumes, efficiency, profitability, and diagnostic accuracy. By unifying imaging and data across the enterprise, Synapse reduces IT fatigue, improves clinical collaboration, enhances patient care, and positions healthcare organizations for future growth. Backed by Fujifilm’s 90-year legacy of innovation, Synapse represents a next-generation enterprise imaging ecosystem that transforms healthcare delivery through intelligence, interoperability, and efficiency.